Oxylipins in fungi


I. Feussner, Georg-August-University Goettingen, Albrecht-von-Haller-Institute for Plant Sciences, Ernst-Caspari-Building, Department of Plant Biochemistry, Justus-von-Liebig-Weg 11, D-37077 Goettingen, Germany
Fax: +49 551395749
Tel: +49 551 395743


In nearly every living organism, metabolites derived from lipid peroxidation, the so-called oxylipins, are involved in regulating developmental processes as well as environmental responses. Among these bioactive lipids, the mammalian and plant oxylipins are the best characterized, and much information about their physiological role and biosynthetic pathways has accumulated during recent years. Although the occurrence of oxylipins and enzymes involved in their biosynthesis has been studied for nearly three decades, knowledge about fungal oxylipins is still scarce as compared with the situation in plants and mammals. However, the research performed so far has shown that the structural diversity of oxylipins produced by fungi is high and, furthermore, that the enzymes involved in oxylipin metabolism are diverse and often exhibit unusual catalytic activities. The aim of this review is to present a synopsis of the oxylipins identified so far in fungi and the enzymes involved in their biosynthesis.