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References

  • 1
    Alvarez-Martinez CE & Christie PJ (2009) Biological diversity of prokaryotic type IV secretion systems. Microbiol Mol Biol Rev 73, 775808.
  • 2
    Suerbaum S & Michetti P (2002) Helicobacter pylori infection. N Engl J Med 347, 11751186.
  • 3
    Fischer W, Karnholz A, Jiménez-Soto LF & Haas R (2008) Type IV secretion systems in Helicobacter pylori. In Helicobacter pylori. Molecular Genetics and Cellular Biology (Yamaoka Y ed.), pp. 115136. Caister Academic Press, Norfolk, UK.
  • 4
    Fischer W, Windhager L, Rohrer S, Zeiller M, Karnholz A, Hoffmann R, Zimmer R & Haas R (2010) Strain-specific genes of Helicobacter pylori: genome evolution driven by a novel type IV secretion system and genomic island transfer. Nucleic Acids Res 38, 60896101.
  • 5
    Gressmann H, Linz B, Ghai R, Pleissner KP, Schlapbach R, Yamaoka Y, Kraft C, Suerbaum S, Meyer TF & Achtman M (2005) Gain and loss of multiple genes during the evolution of Helicobacter pylori. PLoS Genet 1, e43.
  • 6
    Amieva MR & El-Omar EM (2008) Host-bacterial interactions in Helicobacter pylori infection. Gastroenterology 134, 306323.
  • 7
    Hatakeyama M (2008) SagA of CagA in Helicobacter pylori pathogenesis. Curr Opin Microbiol 11, 3037.
  • 8
    Viala J, Chaput C, Boneca IG, Cardona A, Girardin SE, Moran AP, Athman R, Memet S, Huerre MR, Coyle AJ et al. (2004) Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island. Nat Immunol 5, 11661174.
  • 9
    Censini S, Lange C, Xiang Z, Crabtree JE, Ghiara P, Borodovsky M, Rappuoli R & Covacci A (1996) cag, a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors. Proc Natl Acad Sci USA 93, 1464814653.
  • 10
    Akopyants NS, Clifton SW, Kersulyte D, Crabtree JE, Youree BE, Reece CA, Bukanov NO, Drazek ES, Roe BA & Berg DE (1998) Analyses of the cag pathogenicity island of Helicobacter pylori. Mol Microbiol 28, 3753.
  • 11
    Blomstergren A, Lundin A, Nilsson C, Engstrand L & Lundeberg J (2004) Comparative analysis of the complete cag pathogenicity island sequence in four Helicobacter pylori isolates. Gene 328, 8593.
  • 12
    Azuma T, Yamakawa A, Yamazaki S, Ohtani M, Ito Y, Muramatsu A, Suto H, Yamazaki Y, Keida Y, Higashi H et al. (2004) Distinct diversity of the cag pathogenicity island among Helicobacter pylori strains in Japan. J Clin Microbiol 42, 25082517.
  • 13
    Olbermann P, Josenhans C, Moodley Y, Uhr M, Stamer C, Vauterin M, Suerbaum S, Achtman M & Linz B (2010) A global overview of the genetic and functional diversity in the Helicobacter pylori cag pathogenicity island. PLoS Genet 6, e1001069.
  • 14
    Mane SP, Dominguez-Bello MG, Blaser MJ, Sobral BW, Hontecillas R, Skoneczka J, Mohapatra SK, Crasta OR, Evans C, Modise T et al. (2010) Host-interactive genes in Amerindian Helicobacter pylori diverge from their Old World homologs and mediate inflammatory responses. J Bacteriol 192, 30783092.
  • 15
    Farnbacher M, Jahns T, Willrodt D, Daniel R, Haas R, Goesmann A, Kurtz S & Rieder G (2010) Sequencing, annotation, and comparative genome analysis of the gerbil-adapted Helicobacter pylori strain B8. BMC Genomics 11, 335.
  • 16
    McGee DJ, May CA, Garner RM, Himpsl JM & Mobley HL (1999) Isolation of Helicobacter pylori genes that modulate urease activity. J Bacteriol 181, 24772484.
  • 17
    Eppinger M, Baar C, Linz B, Raddatz G, Lanz C, Keller H, Morelli G, Gressmann H, Achtman M & Schuster SC (2006) Who ate whom? Adaptive Helicobacter genomic changes that accompanied a host jump from early humans to large felines. PLoS Genet 2, e120.
  • 18
    Zahrl D, Wagner M, Bischof K, Bayer M, Zavecz B, Beranek A, Ruckenstuhl C, Zarfel GE & Koraimann G (2005) Peptidoglycan degradation by specialized lytic transglycosylases associated with type III and type IV secretion systems. Microbiology 151, 34553467.
  • 19
    Andrzejewska J, Lee SK, Olbermann P, Lotzing N, Katzowitsch E, Linz B, Achtman M, Kado CI, Suerbaum S & Josenhans C (2006) Characterization of the pilin ortholog of the Helicobacter pylori type IV cag pathogenicity apparatus, a surface-associated protein expressed during infection. J Bacteriol 188, 58655877.
  • 20
    Backert S, Fronzes R & Waksman G (2008) VirB2 and VirB5 proteins: specialized adhesins in bacterial type-IV secretion systems? Trends Microbiol 16, 409413.
  • 21
    Buhrdorf R, Förster C, Haas R & Fischer W (2003) Topological analysis of a putative virB8 homologue essential for the cag type IV secretion system in Helicobacter pylori. Int J Med Microbiol 293, 213217.
  • 22
    Kutter S, Buhrdorf R, Haas J, Schneider-Brachert W, Haas R & Fischer W (2008) Protein subassemblies of the Helicobacter pylori Cag type IV secretion system revealed by localization and interaction studies. J Bacteriol 190, 21612171.
  • 23
    Fischer W, Püls J, Buhrdorf R, Gebert B, Odenbreit S & Haas R (2001) Systematic mutagenesis of the Helicobacter pylori cag pathogenicity island: essential genes for CagA translocation in host cells and induction of interleukin-8. Mol Microbiol 42, 13371348. Erratum in: Mol. Microbiol. 47, 1759 (2003).
  • 24
    Selbach M, Moese S, Meyer TF & Backert S (2002) Functional analysis of the Helicobacter pylori cag pathogenicity island reveals both VirD4-CagA-dependent and VirD4-CagA-independent mechanisms. Infect Immun 70, 665671.
  • 25
    Boonjakuakul JK, Canfield DR & Solnick JV (2005) Comparison of Helicobacter pylori virulence gene expression in vitro and in the Rhesus macaque. Infect Immun 73, 48954904.
  • 26
    Sharma CM, Hoffmann S, Darfeuille F, Reignier J, Findeiss S, Sittka A, Chabas S, Reiche K, Hackermüller J, Reinhardt R et al. (2010) The primary transcriptome of the major human pathogen Helicobacter pylori. Nature 464, 250255.
  • 27
    Cendron L & Zanotti G (2011) Structural and functional aspects of unique type IV secretory components in the Helicobacter pylori cag pathogenicity island. FEBS J 278, 12231231.
  • 28
    Fronzes R, Schäfer E, Wang L, Saibil HR, Orlova EV & Waksman G (2009) Structure of a type IV secretion system core complex. Science 323, 266268.
  • 29
    Chandran V, Fronzes R, Duquerroy S, Cronin N, Navaza J & Waksman G (2009) Structure of the outer membrane complex of a type IV secretion system. Nature 462, 10111015.
  • 30
    Terradot L & Waksman G (2011) Architecture of the Helicobacter pylori Cag- Type IV secretion system. FEBS J 278, 12131222.
  • 31
    Lawley TD, Klimke WA, Gubbins MJ & Frost LS (2003) F factor conjugation is a true type IV secretion system. FEMS Microbiol Lett 224, 115.
  • 32
    Nakano N, Kubori T, Kinoshita M, Imada K & Nagai H (2010) Crystal structure of Legionella DotD: insights into the relationship between type IVB and typeII/III secretion systems. PLoS Pathog 6, e1001129.
  • 33
    Pinto-Santini DM & Salama NR (2009) Cag3 is a novel essential component of the Helicobacter pylori Cag type IV secretion system outer membrane subcomplex. J Bacteriol 191, 73437352.
  • 34
    Rohde M, Püls J, Buhrdorf R, Fischer W & Haas R (2003) A novel sheathed surface organelle of the Helicobacter pylori cag type IV secretion system. Mol Microbiol 49, 219234.
  • 35
    Tanaka J, Suzuki T, Mimuro H & Sasakawa C (2003) Structural definition on the surface of Helicobacter pylori type IV secretion apparatus. Cell Microbiol 5, 395404.
  • 36
    Jiménez-Soto LF, Kutter S, Sewald X, Ertl C, Weiss E, Kapp U, Rohde M, Pirch T, Jung K, Retta SF et al. (2009) Helicobacter pylori type IV secretion apparatus exploits β1 integrin in a novel RGD-independent manner. PLoS Pathog 5, e1000684.
  • 37
    Judd PK, Kumar RB & Das A (2005) Spatial location and requirements for the assembly of the Agrobacterium tumefaciens type IV secretion apparatus. Proc Natl Acad Sci USA 102, 1149811503.
  • 38
    Busler VJ, Torres VJ, McClain MS, Tirado O, Friedman DB & Cover TL (2006) Protein–Protein interactions among Helicobacter pylori Cag proteins. J Bacteriol 188, 47874800.
  • 39
    Mossey P, Hudacek A & Das A (2010) Agrobacterium tumefaciens type IV secretion protein VirB3 is an inner membrane protein and requires VirB4, VirB7, and VirB8 for stabilization. J Bacteriol 192, 28302838.
  • 40
    Yeo HJ, Savvides SN, Herr AB, Lanka E & Waksman G (2000) Crystal structure of the hexameric traffic ATPase of the Helicobacter pylori type IV secretion system. Mol Cell 6, 14611472.
  • 41
    Savvides SN, Yeo HJ, Beck MR, Blaesing F, Lurz R, Lanka E, Buhrdorf R, Fischer W, Haas R & Waksman G (2003) VirB11 ATPases are dynamic hexameric assemblies: new insights into bacterial type IV secretion. EMBO J 22, 19691980.
  • 42
    Kwok T, Zabler D, Urman S, Rohde M, Hartig R, Wessler S, Misselwitz R, Berger J, Sewald N, König W et al. (2007) Helicobacter exploits integrin for type IV secretion and kinase activation. Nature 449, 862866.
  • 43
    Tegtmeyer N, Wessler S & Backert S (2011) Role of the cag pathogenicity island encoded type IV secretion system in Helicobacter pylori pathogenesis. FEBS J 278, 11901202.
  • 44
    Nesic D, Miller MC, Quinkert ZT, Stein M, Chait BT & Stebbins CE (2010) Helicobacter pylori CagA inhibits PAR1-MARK family kinases by mimicking host substrates. Nat Struct Mol Biol 17, 130132.
  • 45
    Hohlfeld S, Pattis I, Püls J, Plano GV, Haas R & Fischer W (2006) A C-terminal secretion signal is necessary, but not sufficient for type IV secretion of the Helicobacter pylori CagA protein. Mol Microbiol 59, 16241637.
  • 46
    Murata-Kamiya N, Kikuchi K, Hayashi T, Higashi H & Hatakeyama M (2010) Helicobacter pylori exploits host membrane phosphatidylserine for delivery, localization, and pathophysiological action of the CagA oncoprotein. Cell Host Microbe 7, 399411.
  • 47
    Couturier MR, Tasca E, Montecucco C & Stein M (2006) Interaction with CagF is required for translocation of CagA into the host via the Helicobacter pylori type IV secretion system. Infect Immun 74, 273281.
  • 48
    Pattis I, Weiss E, Laugks R, Haas R & Fischer W (2007) The Helicobacter pylori CagF protein is a type IV secretion chaperone-like molecule that binds close to the C-terminal secretion signal of the CagA effector protein. Microbiology 153, 28962909.
  • 49
    Jurik A, Hausser E, Kutter S, Pattis I, Prassl S, Weiss E & Fischer W (2010) The coupling protein Cagβ and its interaction partner CagZ are required for type IV secretion of the Helicobacter pylori CagA protein. Infect Immun, doi: 10.1128/IAI.00796-10.
  • 50
    Cascales E & Christie PJ (2004) Definition of a bacterial type IV secretion pathway for a DNA substrate. Science 304, 11701173.
  • 51
    Tomb J-F, White O, Kerlavage AR, Clayton RA, Sutton GG, Fleischmann RD, Ketchum KA, Klenk HP, Gill S, Dougherty BA et al. (1997) The complete genome sequence of the gastric pathogen Helicobacter pylori. Nature 388, 539547.
  • 52
    Schröder G, Krause S, Zechner EL, Traxler B, Yeo HJ, Lurz R, Waksman G & Lanka E (2002) TraG-like proteins of DNA transfer systems and of the Helicobacter pylori type IV secretion system: inner membrane gate for exported substrates? J Bacteriol 184, 27672779.
  • 53
    Cendron L, Seydel A, Angelini A, Battistutta R & Zanotti G (2004) Crystal structure of CagZ, a protein from the Helicobacter pylori pathogenicity island that encodes for a type IV secretion system. J Mol Biol 340, 881889.
  • 54
    Cendron L, Tasca E, Seraglio T, Seydel A, Angelini A, Battistutta R, Montecucco C & Zanotti G (2007) The crystal structure of CagS from the Helicobacter pylori pathogenicity island. Proteins 69, 440443.
  • 55
    Bourzac KM, Satkamp LA & Guillemin K (2006) The Helicobacter pylori cag pathogenicity island protein CagN is a bacterial membrane-associated protein that is processed at its C terminus. Infect Immun 74, 25372543.
  • 56
    Cendron L, Couturier M, Angelini A, Barison N, Stein M & Zanotti G (2009) The Helicobacter pylori CagD (HP0545, Cag24) protein is essential for CagA translocation and maximal induction of interleukin-8 secretion. J Mol Biol 386, 204217.
  • 57
    Terradot L, Durnell N, Li M, Li M, Ory J, Labigne A, Legrain P, Colland F & Waksman G (2004) Biochemical characterization of protein complexes from the Helicobacter pylori protein interaction map: strategies for complex formation and evidence for novel interactions within type IV secretion systems. Mol Cell Proteomics 3, 809819.