These authors contributed equally to this study
The prion protein binds thiamine
Article first published online: 15 SEP 2011
© 2011 The Authors Journal compilation © 2011 FEBS
Volume 278, Issue 21, pages 4002–4014, November 2011
How to Cite
Perez-Pineiro, R., Bjorndahl, T. C., Berjanskii, M. V., Hau, D., Li, L., Huang, A., Lee, R., Gibbs, E., Ladner, C., Dong, Y. W., Abera, A., Cashman, N. R. and Wishart, D. S. (2011), The prion protein binds thiamine. FEBS Journal, 278: 4002–4014. doi: 10.1111/j.1742-4658.2011.08304.x
- Issue published online: 21 OCT 2011
- Article first published online: 15 SEP 2011
- Accepted manuscript online: 16 AUG 2011 12:00AM EST
- (Received 20 March 2011, revised 7 August 2011, accepted 11 August 2011)
Figs S1–S6. Stern–Volmer plots for data presented in Table 1.
Fig. S7.15N edited TOCSY-HSQC and NOESY-HSQC strip plots for selected residues in thiamine binding pocket.
Fig. S8. NMR spectra of thiamine (free) and thiamine bound to shPrP.
Table S1. List of human metabolites used in the screening process.
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