Fig. S1. Activation curves of wt P2Y12 after stimulation with ADP and 2MeSADP.

Fig. S2. Activation curves of recombinant P2Y12s with ADP and ADP + 1 μm AR-C66096. (A) wt P2Y12R, (B) E181R, (C) E181D, (D) E181A, (E) E181I, (F) E181Y, (G) R256I, (H) R265K, (I) R265D, (J) R265A, (K) R265F, (L) R265S.

Please note: As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer-reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.

FEBS_8410_sm_FigS1-S2.zip594KSupporting info item

Please note: Wiley Blackwell is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.