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Fig. S1. Overexpression of MyD88, IRAK1, or TRAF6, but not of IRAK4, elicits activation of NF-κB and post-transcriptional regulation via the 165-nucleotide element in HEK293 cells.

Fig. S2. Overexpression of IRAK1, but not of TRAF6, elicits activation of post-transcriptional regulation via the 165-nucleotide element in RAW264.7 cells.

Fig. S3. OHT-mediated activation of the ER(T2) fusion proteins of IRAK1 mutants with a mutation(s) at the ubiquitination site Lys134 and/or Lys180 elicits NF-κB activation and 165-nucleotide element-mediated post-transcriptional activation.

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