Fig. S1. Effect of RNA concentration on globin and EMCV RNA translation.

Fig. S2. Quantification of the Fig.2: Cap dependence of the leader and leaderless mRNA.

Fig. S3. Quantification of the Fig.3: The Expression from synthetic HIV-1 leaderless mRNAs is less dependent on eIF4A.

Fig. S4. Alignment of the NL4.3, patient 4, patient 8 and patient 18 HIV-1 sequences.

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