Molecular mechanism of the allosteric enhancement of the umami taste sensation
Version of Record online: 24 JUL 2012
© 2012 The Authors Journal compilation © 2012 FEBS
The FEBS Journal
Volume 279, Issue 17, pages 3112–3120, September 2012
How to Cite
Mouritsen, O. G. and Khandelia, H. (2012), Molecular mechanism of the allosteric enhancement of the umami taste sensation. The FEBS Journal, 279: 3112–3120. doi: 10.1111/j.1742-4658.2012.08690.x
- Issue online: 21 AUG 2012
- Version of Record online: 24 JUL 2012
- Accepted manuscript online: 5 JUL 2012 02:05PM EST
- (Received 26 March 2012, revised 19 June 2012, accepted 3 July 2012)
Fig. S1. Sequence alignment between the amino acid sequences of the ligand-binding domains of the umami T1R1 subunit and the metabotropic glutamate receptor mGluR1.
Fig. S2. Snapshot of the starting conformations for Movie S1 (simulation NOGlu1).
Fig. S3. Snapshot of the starting conformations for Movie S2 (simulation Glu1).
Fig. S4. Snapshot of the starting conformations for Movie S3 (simulation GMPGlu1).
Movies S1, S2 and S3. Animations showing interpolation between the extreme conformations sampled by the trajectory of NOGlu1, Glu1 and GMPGlu1 projected upon the first eigenvector of the covariance matrix of the backbone heavy atoms.
Please note: As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer-reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
|FEBS_8690_sm_FigS1-S4.zip||10779K||Supporting info item|
Please note: Wiley Blackwell is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.