• 1
    Kris-Etherton PM, Hecker KD, Bonanome A, Coval SM, Binkoski AE, Hilpert KF et al. Bioactive compounds in foods: their role in the prevention of cardiovascular disease and cancer. Am J Med 2002;113:71S88S.
  • 2
    Edris AE. Pharmaceutical and therapeutic potentials of essential oils and their individual volatile constituents: a review. Phytother Res 2007;21:30823.
  • 3
    Paduch R, Kandefer−Szerszeń M, Trytek M, Fiedurek J. Terpenes: substances useful in human healthcare. Arch Immunol Ther Exp 2007;55:113.
  • 4
    Lahlou S, Magalhães PJC, Siqueira RJB, Figueiredo AF, Interaminense LFL, Maia JGS et al. Cardiovascular effects of the essential oil of Aniba canelilla bark in normotensive rats. J Cardiovasc Pharmacol 2005;46:41221.
  • 5
    Shiina Y, Funabashi N, Lee K, Toyoda T, Sekine T, Honjo S et al. Relaxation effects of lavender aromatherapy improve coronary flow velocity reserve in healthy men evaluated by transthoracic Doppler echocardiography. Int J Cardiol 2008;129:1937.
  • 6
    Dayawansa S, Umeno K, Takakura H, Hori E, Tabuchi E, Nagashima Y et al. Autonomic responses during inhalation of natural fragrance of Cedrol in humans. Auton Neurosci 2003;108:7986.
  • 7
    De Sousa DP, Gonçalves JCR, Quintans-Júnior L, Cruz JS, Araújo DAM, Almeida RN. Study of anticonvulsant effect of citronellol, a monoterpene alcohol, in rodents. Neurosci Lett 2006;401:2315.
  • 8
    Abegaz B, Yohannes PG, Dieter RK. Constituents of the essential oil of Ethiopian Cymbopogon citratus Stapf. J Nat Prod 1983;46:4246.
  • 9
    Quintans-Júnior LJ, Souza TT, Leite BS, Lessa NMN, Bonjardim LR, Santos MRV et al. Phythochemical screening and anticonvulsant activity of Cymbopogon winterianus Jowitt (Poaceae) leaf essential oil in rodents. Phytomedicine 2008;15:61924.
  • 10
    Tavares ES, Julião LS, Lopes D, Bizzo HR, Lage CLS, Leitão SG. Análise do óleo essencial de folhas de três quimiotipos de Lippia alba (Mill.) N. E. Br. (Verbenaceae) cultivados em condições semelhantes. Braz J Pharmacog 2005;15:15.
  • 11
    Lahlou S, Carneiro-Leão RF, Leal-Cardoso JH. Cardiovascular effects of the essential oil of Mentha x villosa in DOCA-salt-hypertensive rats. Phytomedicine 2002;9:71520.
  • 12
    Chan W, Yao X, Ko W, Huang Y. Nitric oxide mediated endothelium-dependent relaxation induced by glibenclamide in rat isolated aorta. Cardiovasc Res 2000;46:1807.
  • 13
    Mitchelson F. Heterogeneity in muscarinic receptors: evidence from pharmacological studies with antagonists. Trends Pharmacol Sci 1984;5:126.
  • 14
    Moncada S, Palmer RMJ, Higgs EA. Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol Rev 1991;43:10942.
  • 15
    Clark SG, Fuchs LC. Role of nitric oxide and Ca++-dependent K+ channels in mediating heterogeneous microvascular responses to acetylcholine in different vascular beds. J Pharmacol Exp Ther 1997;282:14739.
  • 16
    Takahashi T, Owyang C. Characterization of vagal pathways mediating gastric accommodation reflex in rats. J Physiol 1997;504:47988.
  • 17
    Menezes IAC, Moreira IJA, Carvalho AA, Antoniolli AR, Santos MRV. Cardiovascular effects of the aqueous extract from Caesalpinia ferrea: involvement of ATP-sensitive potassium channels. Vasc Pharmacol 2007;47:417.
  • 18
    Cook NS. Effect of some potassium channel blockers on contractile responses of the rabbit aorta. J Cardiovasc Pharmacol 1989;13:299306.
  • 19
    Santos MRV, Carvalho AA, Medeiros IA, Alves PB, Marchioro M, Antoniolli AR. Cardiovascular effects of Hyptis fruticosa essential oil in rats. Fitoterapia 2007;78:18691.
  • 20
    Sakata K, Karaki H. Effects of a novel smooth muscle relaxant, KT–362, on contraction on cytosolic Ca2+ level in the rat aorta. Br J Pharmacol 1991;102:1748.
  • 21
    Adaramoye OA, Anjos RM, Almeida MM, Veras RC, Silvia DF, Oliveira FA et al. Hypotensive and endothelium-independent vasorelaxant effects of methanolic extract from Curcuma longa L. in rats. J Ethnopharmacol 2009;124:45762.
  • 22
    Sociedade Brasileira de Cardiologia. V Diretrizes Brasileiras de Hipertensão Arterial. Arq Bras Cardiol 2007;89:e2479.
  • 23
    White RM, Rivera CO, Davison CB. Differential contribution of endothelial function to vascular reactivity in conduit and resistance arteries from deoxycorticosterone-salt hypertensive rats. Hypertension 1996;27:124553.
  • 24
    Lahlou S, Leal-Cardoso JH, Magalhães PJ. Essential oil of Croton nepetaefolius decreases blood pressure through an action upon vascular smooth muscle: studies in DOCA-salt hypertensive rats. Planta Med 2000;66:13843.
  • 25
    Lahlou S, Carneiro-Leao RF, Leal-Cardoso JH, Toscano CF. Cardiovascular effects of the essential oil of Mentha x villosa and its main constituent, piperitenone oxide, in normotensive anaesthetised rats: role of the autonomic nervous system. Planta Med 2001;67:63843.
  • 26
    McGuill MW, Rowan AN. Biological effects of blood loss: implications for sampling volumes and techniques. ILAR J 1989;31:518.
  • 27
    Gurney AM. Mechanisms of drug-induced vasodilatation. Pharm Pharmacol 1994;46:24251.
  • 28
    Münzel T, Feil R, Mülsch A, Lohmann SM, Hofmann F, Walter U. Physiology and pathophysiology of vascular signaling controlled by cyclic guanosine 3′,5′-cyclic monophosphate-dependent protein kinase. Circulation 2003;108:217283.
  • 29
    Karaki H, Weiss GB. Calcium release in smooth muscle. Life Sci 1998;42:11122.
  • 30
    Somlyo AV, Bond M, Somlyo AP, Scarpa A. Inositol trisphosphate-induced calcium release and contraction in vascular smooth muscle. Proc Natl Acad Sci U S A 1985;82:52315.
  • 31
    Missiaen L, Parys JB, De Smedt H, Himpens B, Casteels R. Inhibition of inositol trisphosphate-induced calcium release by caffeine is prevented by ATP. Biochem J 1994;300:814.
  • 32
    Lahlou S, Galindo CA, Leal-Cardoso JH, Fonteles MC, Duarte GP. Cardiovascular effects of the essential oil of Alpinia zerumbet leaves and its main constituent, Terpinen-4-ol, in rats: role of the autonomic nervous system. Planta Med 2002;68:1097102.
  • 33
    Aydin Y, Kutlay O, Ari S, Duman S, Uzuner K, Aydin S. Hypotensive effects of carvacrol on the blood pressure of normotensive rats. Planta Med 2007;73:136571.
  • 34
    Guedes DN, Silva DF, Barbosa-Filho JM, Medeiros IA. Calcium antagonism and the vasorelaxation of the rat aorta induced by rotundifolone. Braz J Med Biol Res 2004;37:18817.