Caring for patients with an eating disorder (ED) is associated with a high level of burden and psychological distress. Currently, the Eating Disorder Symptom Impact Scale (EDSIS) is the only scale that measures the specific impact of caring for a patient with an ED. The initial development study within a British sample of carers indicated that the EDSIS has a four-factor structure. The aim of the current study was to confirm the factor structure of the EDSIS within an Australian sample of carers. One hundred and fifty-four carers completed the EDSIS. In contrast to the initial study, a six-factor structure was derived explaining 69.66% of the variance: guilt, social isolation, confrontational behaviours, binge–purge difficulties, mealtime difficulties, and illness awareness. Reliability was acceptable (Cronbach's alpha range 0.69–0.88). Five of the six factors were moderately correlated with the General Health Questionnaire-12 (r range = 0.24–0.51). A six-factor solution may be a valid alternative for the EDSIS.