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CASE REPORT: Association Between Erectile Dysfunction and Coronary Artery Disease: A Case Report Study

Authors

  • Piero Montorsi MD,

    1. Institute of Cardiology University of Milan, Centro Cardiologico Monzino, IRCCS, Milan, Italy
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  • Paolo M. Ravagnani MD,

    1. Institute of Cardiology University of Milan, Centro Cardiologico Monzino, IRCCS, Milan, Italy
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  • Stefano Galli MD,

    1. Institute of Cardiology University of Milan, Centro Cardiologico Monzino, IRCCS, Milan, Italy
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  • Alberto Briganti MD,

    1. Department of Urology and Sexual Diseases, Università Vita-Salute, San Raffaele Hospital, Milan, Italy
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  • Andrea Salonia MD,

    1. Department of Urology and Sexual Diseases, Università Vita-Salute, San Raffaele Hospital, Milan, Italy
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  • Federico Dehò MD,

    1. Department of Urology and Sexual Diseases, Università Vita-Salute, San Raffaele Hospital, Milan, Italy
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  • Claude Schulman MD,

    1. Department of Urology, Erasme Hospital, University Clinics of Brussels, Brussels, Belgium
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  • Francesco Montorsi MD

    Corresponding author
    1. Department of Urology and Sexual Diseases, Università Vita-Salute, San Raffaele Hospital, Milan, Italy
      Francesco Montorsi, Cattedra  di  Urologia,  Universita’ Vita  e  Salute,  Ospedale San Raffaele, Via Olgettina 60, 20132 Milan, Italy. Tel: (39) 02-26437286; Fax: (39) 02-26437298; E-mail: montorsi.francesco@hsr.it
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Francesco Montorsi, Cattedra  di  Urologia,  Universita’ Vita  e  Salute,  Ospedale San Raffaele, Via Olgettina 60, 20132 Milan, Italy. Tel: (39) 02-26437286; Fax: (39) 02-26437298; E-mail: montorsi.francesco@hsr.it

ABSTRACT

Evidence is accumulating in favor of classifying erectile dysfunction (ED) as a vascular disorder. There are three main clinical scenarios in which ED and coronary artery disease (CAD) may coexist: the patient with ED who later develops CAD, the patient with overt CAD who is casually found to have ED, and the patient with acute coronary syndrome who has normal sexual function. This study presents three cases and discusses a “putative” pathophysiological mechanism underlying all these clinical presentations. Further studies, coupling functional and structural changes of coronary circulation with those of penile (i.e., dynamic penile test) circulation in each of these situations are mandatory to support this hypothesis.

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