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Male Anorgasmia Treated with Oxytocin

Authors

  • Waguih William IsHak MD, FAPA,

    Corresponding author
    1. Cedars-Sinai Medical Center—Psychiatry, Los Angeles, CA, USA;
    2. University of California at Los Angeles (UCLA)—Psychiatry, Los Angeles, CA, USA;
      Waguih William IsHak, MD, FAPA, Cedars-Sinai Medical Center—Psychiatry, 8730 Alden Dr, Thalians W-157, Los Angeles, CA 90048, USA. Tel: 310-423-3515; Fax: 310-423-3947; E-mail: waguih.ishak@cshs.org
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  • Daniel S. Berman MD,

    1. Cedars-Sinai Medical Center—Cardiology, Los Angeles, CA, USA;
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  • Anne Peters MD

    1. Endocrinology, University of Southern California, Keck School of Medicine, Los Angeles, CA, USA
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Waguih William IsHak, MD, FAPA, Cedars-Sinai Medical Center—Psychiatry, 8730 Alden Dr, Thalians W-157, Los Angeles, CA 90048, USA. Tel: 310-423-3515; Fax: 310-423-3947; E-mail: waguih.ishak@cshs.org

ABSTRACT

Introduction.  This is a case report on male anorgasmia that was successfully treated with oxytocin. Oxytocin is increased during arousal and peaks during orgasm. More recently, a study on humans published in Nature has shown its value in social bonding, increasing trust, and enhancing the sense of well-being.

Aim.  To test the effectiveness of administering oxytocin in a case of treatment-resistant anorgasmia.

Methods.  The patient underwent a biopsychosocial evaluation by a psychiatrist trained in sexual medicine and sex therapy for male orgasmic disorder, acquired type. Medical conditions, effect of substances, and psychological issues were ruled out. The patient was properly consented to using oxytocin as an off-label trial. Oxytocin was administered using a nasal spray intracoitally because of its ultra-short half-life.

Results.  Oxytocin was effective in restoring ejaculation.

Conclusions.  A case of treatment-resistant male anorgasmia was successfully treated with intracoital administration of intranasal oxytocin. Ishak WW, Berman DS, and Peters A. Male anorgasmia treated with oxytocin. J Sex Med 2008;5:1022–1024.

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