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Risk Factors for Erectile Dysfunction in Patients with Urethral Strictures Secondary to Blunt Trauma


Yue-Min Xu, MD, PhD, Department of Urology, Sixth People's Hospital, Jiao Tong University of Shanghai, 600 Yi Shan Road, Shanghai 200233, China. Tel: (86) 21-64369181; Fax: (86) 21-64083783; E-mail:


Introduction.  Erectile dysfunction (ED) is a well-known consequence of pelvic fracture, particularly in cases involving urethral injury. There are several risk factors that may be related to ED. However, no systemic approach is used to assess erectile function secondary to urethral trauma.

Aim.  To investigate ED associated with urethral injury secondary to pelvic fracture and perineal trauma.

Methods.  Forty patients with traumatic urethral strictures secondary to blunt traumatic impact episode to the pelvis or perineum were included in our study. Pelvic fractures and urethral strictures were categorized according to injury types and radiological findings. All patients underwent nocturnal penile tumescence (NPT) monitoring, dynamic color-duplex Doppler ultrasonography (D-CDDU) before surgery. NPT monitoring was conducted again after surgery.

Main Outcome Measures.  The events of NPT and D-CDDU were recorded.

Results.  In all patients, 11 had organic ED demonstrated by NPT. Vascular pathology was identified in three of 11 patients (27%). The peak systolic velocity of cavernosal artery was lower in patients with pubic diastasis in comparison to those without diastasis (P < 0.05). Significant changes in penile length and circumference were noted in posterior urethral injury compared with anterior urethral injury during erection (P < 0.05). The erectile duration time has a similar statistical difference in two groups mentioned above. However, no significant difference could be observed in the end-to-end anatomosis procedure before and after surgery (P > 0.05).

Conclusions.  The pelvic fracture type, especially pubic diastasis, is a risk factor for ED following urethral injury. Location of the stricture is also a risk factor for subsequent erectile dysfunction. Feng C, Xu Y-M, Yu J-J, Fei X-F, and Chen L. Risk factors for erectile dysfunction in patients with urethral strictures secondary to blunt trauma. J Sex Med 2008;5:2656–2661.