Tolterodine Immediate Release Improves Sexual Function in Women with Overactive Bladder
Article first published online: 10 SEP 2008
© 2008 International Society for Sexual Medicine
The Journal of Sexual Medicine
Volume 5, Issue 12, pages 2880–2885, December 2008
How to Cite
Hajebrahimi, S., Azaripour, A. and Sadeghi-Bazargani, H. (2008), Tolterodine Immediate Release Improves Sexual Function in Women with Overactive Bladder. Journal of Sexual Medicine, 5: 2880–2885. doi: 10.1111/j.1743-6109.2008.00976.x
- Issue published online: 3 DEC 2008
- Article first published online: 10 SEP 2008
- Overactive Bladder;
- Sexual Function;
Introduction. Quality of life studies indicate that overactive bladder (OAB) has a greater negative impact on everyday life than other serious conditions such as diabetes. The detrimental effect of OAB on female sexual health is more prominent than urinary incontinence. We know that tolterodine immediate release (IR) has a beneficial effect on urinary symptoms in OAB.
Aim. To evaluate the impact of tolterodine IR on sexual function in patients with OAB.
Methods. A total of 30 sexually active women with OAB from 20 to 52 years were included. All patients filled out the International Consultation on Incontinence Questionnaire (ICIQ) and the Arizona Sexual Experience Scale (ASEX) before treatment with tolterodine IR and at the end of each month of treatment until 3 months.
Main Outcome Measures. Expected outcomes were improvements in the ICIQ and ASEX total score. All ASEX items were expected to improve individually. These improvements indicate better sexual function after treatment.
Results. The mean of the total ASEX score improved relative to baseline in the first (P < 0.01), second (P < 0.01), and third (P < 0.01) follow-up. The mean of scores for sexual desire, arousal, vaginal lubrication, orgasm, and orgasm satisfaction improved significantly (P < 0.01) with each follow-up.
Conclusion. Tolterodine IR significantly improves sexual function of women with OAB. Improvement is seen in all domains of sexual function. Hajebrahimi S, Azaripour A, and Sadeghi-Bazargani H. Tolterodine Immediate Release improves sexual function in women with overactive bladder. J Sex Med **;**:**–**.