Improved Erectile Function after Cardiac Resynchronization Therapy in a Patient with Heart Failure—A Case Report


Ernst R. Schwarz, MD, PhD, FESC, FACC, FSCAI, Cedars Sinai Heart Institute, 8700 Beverly Boulevard, Suite 6215, Los Angeles, CA 90048, USA. Tel: (310) 423-1866; Fax: (310) 423-1498; E-mail:


Introduction.  Erectile dysfunction (ED) is very common among heart failure patients and has a very dramatic, negative impact on patients' quality of life. Both ED and heart failure have several risk factors in common; however, little data exist on the correlation between the heart failure-targeted interventions and improvement of ED.

Aim.  To report a case of improved sexual function after cardiac resynchronization.

Methods.  We report the case of a 63-year-old man with ischemic cardiomyopathy and long-standing ED, who experienced significant improvement of his sexual function following biventricular pacing device implantation. Notably, earlier interventions attempting to improve his ED, namely, heart failure medication adjustments and phosphodiesterase-5 inhibitors, have failed.

Results.  Following cardiac resynchronization therapy, patient's erectile function improved without any other ED-specific treatment.

Conclusions.  To the best of our knowledge, this is the first report of improved sexual function in a patient with heart failure and ED following cardiac resynchronization therapy. Although the exact mechanisms remain unknown, we believe that cardiac resynchronization improves ED through improved cardiac and endothelial function. Domanski D, Rosanio S, and Schwarz ER. Improved erectile function after cardiac resynchronization therapy in a patient with heart failure—a case report. J Sex Med 2009;6:2910–2914.