• 1
    Population Division of the Department of Economic and Social Affairs of the United Nations Secretariat. World Population Prospects: The 2006 Revision and World Urbanization Prospects: The 2005 Revision. Available at: (accessed September 21, 2009).
  • 2
    WHO Regional Office for Europe. Atlas of Health in Europe 2nd edition 2008. Available at: (accessed September 21, 2009).
  • 3
    Mathers CD, Sadana R, Salomon JA, Murray CJ, Lopez AD. Healthy life expectancy in 191 countries, 1999. Lancet 2001;357:168591.
  • 4
    Murray CJ, Lopez AD. Alternative projections of mortality and disability by cause 1990–2020: Global Burden of Disease Study. Lancet 1997;349:1498504.
  • 5
    Jagger C, Gillies C, Moscone F, Cambois E, Van Oyen H, Nusselder W, Robine JM, EHLEIS Team. Inequalities in healthy life years in the 25 countries of the European Union in 2005: A cross-national meta-regression analysis. Lancet 2008;372:212431.
  • 6
    Lopez AD, Mathers CD, Ezzati M, Jamison DT, Murray CJ. Global and regional burden of disease and risk factors, 2001: Systematic analysis of population health data. Lancet 2006;367:174757.
  • 7
    Mackenbach JP, Stirbu I, Roskam AJ, Schaap MM, Menvielle G, Leinsalu M, Kunst AE, European Union Working Group on Socioeconomic Inequalities in Health. Socioeconomic inequalities in health in 22 European countries. N Engl J Med 2008;358:246881.
  • 8
    Yusuf S, Hawken S, Ounpuu S, Dans T, Avezum A, Lanas F, McQueen M, Budaj A, Pais P, Varigos J, Lisheng L, INTERHEART Study Investigators. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): Case-control study. Lancet 2004;364:93752.
  • 9
    Montorsi P, Ravagnani PM, Galli S, Salonia A, Briganti A, Werba JP, Montorsi F. Association between erectile dysfunction and coronary artery disease: Matching the right target with the right test in the right patient. Eur Urol 2006;50:72131.
  • 10
    Mäkinen JI, Perheentupa A, Raitakari OT, Koskenvuo M, Pöllänen P, Mäkinen J, Huhtaniemi I. Sexual symptoms in aging men indicate poor life satisfaction and increased health service consumption. Urology 2007;70:11949.
  • 11
    Jackson G, Rosen RC, Kloner RA, Kostis JB. The second Princeton consensus on sexual dysfunction and cardiac risk: New guidelines for sexual medicine. J Sex Med 2006;3:2836.
  • 12
    DeRogatis LR, Burnett AL. The epidemiology of sexual dysfunctions. J Sex Med 2008;5:289300.
  • 13
    Lee DM, O'Neill TW, Pye SR, Silman AJ, Finn JD, Pendleton N, Tajar A, Bartfai G, Casanueva F, Forti G, Giwercman A, Huhtaniemi IT, Kula K, Punab M, Boonen S, Vanderschueren D, Wu FC; EMAS study group. The European Male Ageing Study (EMAS): Design, methods and recruitment. Int J Androl 2009;32:1124.
  • 14
    O'Connor DB, Corona G, Forti G, Tajar A, Lee DM, Finn JD, Bartfai G, Boonen S, Casanueva F, Giwercman A, Huhtaniemi IT, Kula K, O'Neill TW, Punab M, Silman AJ, Vanderschueren D, Wu FCW, the EMAS Study Group. Assessment of sexual health in ageing men in Europe: Development and validation of the European Male Ageing Study (EMAS) Sexual Function Questionnaire (EMAS-SFQ). J Sex Med 2008;5:137485.
  • 15
    Fister K, McKee M. Health and health care in transitional Europe. BMJ 2005;331:16970.
  • 16
    Shkolnikov VM, Andreev EM, Jasilionis D, Leinsalu M, Antonova OI, McKee M. The changing relation between education and life expectancy in central and eastern Europe in the 1990s. J Epidemiol Community Health 2006;60:87581.
  • 17
    Gaziano TA, Opie LH, Weinstein MC. Cardiovascular disease prevention with a multidrug regimen in the developing world: A cost-effectiveness analysis. Lancet 2006;368:67986.
  • 18
    NIH Consensus Conference. Impotence. NIH Consensus Development Panel on Impotence. JAMA 1993;270:8390.
  • 19
    Lue TF, Giuliano F, Montorsi F, Rosen RC, Andersson KE, Althof S, Christ G, Hatzichristou D, Hirsch M, Kimoto Y, Lewis R, McKenna K, MacMahon C, Morales A, Mulcahy J, Padma-Nathan H, Pryor J, De Tejada IS, Shabsigh R, Wagner G. Summary of the recommendations on sexual dysfunctions in men. J Sex Med 2004;1:623.
  • 20
    Rosen R, Altwein J, Boyle P, Kirby RS, Lukacs B, Meuleman E, O'Leary MP, Puppo P, Robertson C, Giuliano F. Lower urinary tract symptoms and male sexual dysfunction: The Multinational Survey of the Aging Male (MSAM-7). Eur Urol 2003;44:63749.
  • 21
    Nicolosi A, Moreira ED Jr, ShiraiM, Bin Mohd TambiMI, GlasserDB. Epidemiology of erectile dysfunction in four countries: Cross-national study of the prevalence and correlates of erectile dysfunction. Urology 2003;61:2016.
  • 22
    Rosen RC, Fisher WA, Eardley I, Niederberger C, Nadel A, Sand M, Men's Attitudes to Life Events and Sexuality (MALES) Study. The multinational Men's Attitudes to Life Events and Sexuality (MALES) study: I. Prevalence of erectile dysfunction and related health concerns in the general population. Curr Med Res Opin 2004;20:60717.
  • 23
    Nicolosi A, Laumann EO, Glasser DB, Moreira ED Jr, PaikA, GingellC, Global Study of Sexual Attitudes and Behaviors Investigators' Group. Sexual behavior and sexual dysfunctions after age 40: The global study of sexual attitudes and behaviors. Urology 2004;64:9917.
  • 24
    Shabsigh R, Perelman MA, Lockhart DC, Lue TF, Broderick GA. Health issues of men: Prevalence and correlates of erectile dysfunction. J Urol 2005;174:6627.
  • 25
    Laumann EO, Nicolosi A, Glasser DB, Paik A, Gingell C, Moreira E, Wang T; GSSAB Investigators' Group. Sexual problems among women and men aged 40–80 y: Prevalence and correlates identified in the Global Study of Sexual Attitudes and Behaviors. Int J Impot Res 2005;17:3957.
  • 26
    Giuliano F, Chevret-Measson M, Tsatsaris A, Reitz C, Murino M, Thonneau P. Prevalence of erectile dysfunction in France: Results of an epidemiological survey of a representative sample of 1004 men. Eur Urol 2002;42:3829.
  • 27
    Braun M, Wassmer G, Klotz T, Reifenrath B, Mathers M, Engelmann U. Epidemiology of erectile dysfunction: Results of the “Cologne Male Survey.” Int J Impot Res 2000;12:30511.
  • 28
    Petrone L, Mannucci E, Corona G, Bartolini M, Forti G, Giommi R, Maggi M. Structured Interview on Erectile Dysfunction (SIEDY©): A new, multi-dimensional instrument for quantification of pathogenetic issues on erectile dysfunction. Int J Impot Res 2003;15:21020.
  • 29
    Laumann EO, Waite LJ. Sexual dysfunction among older adults: Prevalence and risk factors from a nationally representative U.S. probability sample of men and women 57–85 years of age. J Sex Med 2008;5:230011.
  • 30
    Khoo EM, Tan HM, Low WY. Erectile dysfunction and comorbidities in aging men: An urban cross-sectional study in Malaysia. J Sex Med 2008;5:292534.
  • 31
    Bitzer J, Platano G, Tschudin S, Alder J. Sexual counseling in elderly couples. J Sex Med 2008;5:202743.
  • 32
    Perelman M, Shabsigh R, Seftel A, Althof S, Lockhart D. Attitudes of men with erectile dysfunction: A cross-national survey. J Sex Med 2005;2:397406.
  • 33
    Low WY, Wong YL, Zulkifli SN, Tan HM. Malaysian cultural differences in knowledge, attitudes and practices related to erectile dysfunction: Focus group discussions. Int J Impot Res 2002;14:4405.
  • 34
    Ormel J, VonKorff M, Ustun TB, Pini S, Korten A, Oldehinkel T. Common mental disorders and disability across cultures. Results from the WHO Collaborative Study on Psychological Problems in General Health Care. JAMA 1994;272:17418.
  • 35
    Araki I, Tsuchida T, Nomura T, Fukasawa M, Takihana Y, Koyama N, Takeda M. Differential impact of lower urinary tract symptoms on generic and disease-specific quality of life in men and women. Urol Int 2008;81:605.
  • 36
    Althof SE. Quality of life and erectile dysfunction. Urology 2002;59:80310.
  • 37
    Holden CA, McLachlan RI, Pitts M, Cumming R, Wittert G, Agius PA, Handelsman DJ, De Kretser DM. Men in Australia Telephone Survey (MATeS): A national survey of the reproductive health and concerns of middle-aged and older Australian men. Lancet 2005;366:21824.
  • 38
    Lindau ST, Schumm LP, Laumann EO, Levinson W, O'Muircheartaigh CA, Waite LJ. A study of sexuality and health among older adults in the United States. N Engl J Med 2007;357:76274.
  • 39
    Gades NM, Jacobson DJ, McGree ME, St Sauver JL, Lieber MM, Nehra A, Girman CJ, Jacobsen SJ. Longitudinal evaluation of sexual function in a male cohort: The Olmsted County study of Urinary Symptoms and Health Status among Men. J Sex Med 2009;6:245566.
  • 40
    Beckman N, Waern M, Gustafson D, Skoog I. Secular trends in self reported sexual activity and satisfaction in Swedish 70 year olds: Cross sectional survey of four populations, 1971–2001. BMJ 2008;337:a279.
  • 41
    Corona G, Forti G, Maggi M. Why can patients with erectile dysfunction be considered lucky? The association with testosterone deficiency and metabolic syndrome. Aging Male 2008;11:1939.
  • 42
    Corona G, Ricca V, Bandini E, Mannucci E, Petrone L, Fisher AD, Lotti F, Balercia G, Faravelli C, Forti G, Maggi M. Association between psychiatric symptoms and erectile dysfunction. J Sex Med 2008;5:45868.
  • 43
    Corona G, Mannucci E, Mansani R, Petrone L, Bartolini M, Giommi R, Forti G, Maggi M. Organic, relational and psychological factors in erectile dysfunction in men with diabetes mellitus. Eur Urol 2004;46:2228.