Flibanserin and 8-OH-DPAT Implicate Serotonin in Association between Female Marmoset Monkey Sexual Behavior and Changes in Pair-Bond Quality
Article first published online: 3 FEB 2012
© 2012 International Society for Sexual Medicine
The Journal of Sexual Medicine
Volume 9, Issue 3, pages 694–707, March 2012
How to Cite
Aubert, Y., Gustison, M. L., Gardner, L. A., Bohl, M. A., Lange, J. R., Allers, K. A., Sommer, B., Datson, N. A. and Abbott, D. H. (2012), Flibanserin and 8-OH-DPAT Implicate Serotonin in Association between Female Marmoset Monkey Sexual Behavior and Changes in Pair-Bond Quality. Journal of Sexual Medicine, 9: 694–707. doi: 10.1111/j.1743-6109.2011.02616.x
- Issue published online: 28 FEB 2012
- Article first published online: 3 FEB 2012
Figure S1 24-hour pharmacokinetic profiles of 10 mg/kg and 30 mg/kg flibanserin in female marmoset monkeys. Flibanserin was administered PO at doses of 10 mg/kg or 30 mg/kg. Blood samples were taken at 0.25 h, 0.5 h, 1 h, 3 h, 6 h and 24 h after flibanserin administration and analyzed for circulating flibanserin concentrations. Flibanserin doses did not significantly differ (P > 0.05; N = 4).
Table S1 In a dose-response study, the behavioral effects of 10 mg/kg or 30 mg/kg flibanserin, administered to female marmosets, were compared to respective baseline behavior of each individual. Difference between flibanserin doses were assessed by three-way ANOVA including the dose of flibanserin as between-subject factor
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