Ovarian hyperstimulation syndrome
Correspondence: Raj Mathur. Email: email@example.com
- Ovarian hyperstimulation syndrome (OHSS) is characterised by ovarian enlargement, increased vascular permeability and fluid shift.
- Patients with polycystic ovary syndrome (PCOS) or previous history of OHSS are at increased risk.
- A reduced risk of OHSS is seen with use of gonadotrophin-releasing hormone antagonist instead of agonist, coasting of overstimulated cycles, metformin in women with PCOS and dopamine agonists.
- OHSS is likely to be more severe and prolonged in cycles where conception occurs.
- Patients of severe OHSS require close monitoring of fluid balance, thromboprophylaxis and attention to effusions.
- To identify patients and cycles at high risk of OHSS and apply preventative measures.
- To assess and classify the severity of OHSS.
- To manage cases of severe OHSS.
- How do we counsel patients about the risk of an uncommon serious complication of fertility treatment in the face of an overwhelming desire to have a family?
- Should the risk of OHSS be considered a reason to restrict funding for assisted conception treatment?