Human growth hormone treatment: Synthesis of literature on product delivery systems and administration practices


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Purpose.  To synthesize current literature on recombinant human growth hormone (rhGH) use and to identify areas of research that have received little to no attention in light of administration practice and patient perception/behavior.

Design and Methods.  Relevant articles for a systematic review were identified through PubMed.

Results.  A total of 43 articles were identified: 9 (15.9%) studies on product administration practices and 34 (84.1%) on patient behavior patterns. Patients primarily preferred simple, convenient, and easy-to-use delivery devices. However, literature addressing the effect of convenient product administration practices on treatment outcomes using real-world patient/caregiver data is lacking.

Practice Implications.  Better understanding of real-world product administration practices will help nurses identify areas of improvement in patient education and training.