Laurence A. Levine is a consultant with Pfizer, Lilly, American Medical Systems, Auxilium and Coloplast, a speaker for Pfizer, Lilly, Coloplast and Auxilium, and an investigator with fsPhysioMed and Auxilium.
Non-surgical therapy of Peyronie's disease
Article first published online: 28 DEC 2007
Asian Journal of Andrology
Volume 10, Issue 1, pages 79–87, January 2008
How to Cite
Taylor, F. L. and Levine, L. A. (2008), Non-surgical therapy of Peyronie's disease. Asian Journal of Andrology, 10: 79–87. doi: 10.1111/j.1745-7262.2008.00351.x
- Issue published online: 28 DEC 2007
- Article first published online: 28 DEC 2007
- Peyronie's disease;
- penile induration;
- injections intralesional;
- vitamin E;
- amino acids
The present paper provides a review of the available non-surgical treatments for Peyronie's disease (PD). A review of published literature on oral, intralesional, external energy and iontophoresis therapies for PD was performed, and the published results of available treatment options reviewed. The authors' recommendations for appropriate non-surgical management of PD are provided. Although there are many published reports that show the efficacy of non-surgical therapies for PD, there is a lack of large scale, multicenter controlled clinical trials, which makes treatment recommendations difficult. Careful review of the literature does suggest that there are treatment options that make scientific sense and appear to stabilize the disease process, reduce deformity, and improve function. Offering no treatment at all will encourage our patients to pursue alternative treatments, which might do harm, and misses the opportunity to do some good. Clearly further work is necessary to develop safe and effective non-surgical treatments for PD.