From genome to proteome: great progress in the domesticated silkworm (Bombyx mori L.)


  • This work was supported by the grants from the National Basic Research Program of China (No. 2005CB121003), the National Hi-Tech Research and Development Program of China (No. 2006AA10A118), the National Postdoctoral Fund of China (No. 20070411197) and the Doctoral Fund of the Ministry of Education of China (No. 20070335148)

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As the only truly domesticated insect, the silkworm not only has great economic value, but it also has value as a model for genetics and molecular biology research. Genomics and proteomics have recently shown vast potential to be essential tools in domesticated silkworm research, especially after the completion of the Bombyxmori genome sequence. This paper reviews the progress of the domesticated silkworm genome, particularly focusing on its genetic map, physical map and functional genome. This review also presents proteomics, the proteomic technique and its application in silkworm research.