Common complaints, difficult diagnosis: Multiple myeloma
Article first published online: 2 MAY 2006
2006 American Academy of Nurse Practitioners
Journal of the American Academy of Nurse Practitioners
Volume 18, Issue 5, pages 190–194, May 2006
How to Cite
Dvorak, C. (2006), Common complaints, difficult diagnosis: Multiple myeloma. Journal of the American Academy of Nurse Practitioners, 18: 190–194. doi: 10.1111/j.1745-7599.2006.00122.x
- Issue published online: 2 MAY 2006
- Article first published online: 2 MAY 2006
- Received: July 2005; accepted: November 2005
- Nurse practitioner;
- multiple myeloma;
- differential diagnosis
Purpose: To review the presenting signs and symptoms of multiple myeloma, its pathophysiology, diagnostic evaluation, and treatment options.
Data sources: A literature review of research articles and publications by oncology experts who specialize in multiple myeloma, supplemented by a case study.
Conclusions: Multiple myeloma is a cancer of the geriatric population, with the average age at diagnosis between 65 and 68 years. As the population of those over age 65 is predicted to double by the year 2050, the incidence of myeloma is expected to increase. Nurse practitioners (NPs) must become familiar with the signs, symptoms, and complications of myeloma for patients to be diagnosed and referred to specialists in a timely manner.
Implications for practice: Patients with multiple myeloma often present with vague, common symptoms such as back pain, bony pain, fatigue, and anemia. These symptoms may be treated as separate medical conditions if NPs fail to include multiple myeloma in their differential diagnosis. If NPs are educated on this malignancy, they will have the expertise to look for other signs of the disease such as hypercalcemia, pathological fractures, osteopenia, or renal failure. Without early recognition of multiple myeloma and referrals to oncology specialists, patients are left with a delayed diagnosis and poor symptom control.