Anal Pap smears: Should we be doing them?
Article first published online: 28 JUL 2009
© 2009 The Author(s). Journal compilation © 2009 American Academy of Nurse Practitioners
Journal of the American Academy of Nurse Practitioners
Volume 21, Issue 8, pages 437–443, August 2009
How to Cite
Lindsey, K., DeCristofaro, C. and James, J. (2009), Anal Pap smears: Should we be doing them?. Journal of the American Academy of Nurse Practitioners, 21: 437–443. doi: 10.1111/j.1745-7599.2009.00433.x
- Issue published online: 28 JUL 2009
- Article first published online: 28 JUL 2009
- Received: March 2008; accepted: July 2008
- Human papilloma virus;
- HPV infection;
- anal Pap smears;
- cervical Pap smears;
- genital warts;
- anal cancer;
- receptive anal intercourse;
- early detection HPV;
- anal cancer prevention
Purpose: To identify the need to perform anal Papanicolau (Pap) smears for diagnosing histologic changes associated with human papilloma virus (HPV) infection in order to provide early intervention for the prevention of anal cancer. To offer the primary care provider information, based on evidence-based research, about identifying the high-risk patient using risk factors, instructions on performing the anal Pap smear, interpreting the results, and initiating treatment interventions and/or referrals for care. Additionally, the possibility of an HPV vaccine for men will be discussed.
Data Sources: Evidence-based literature, theoretical framework, and peer-reviewed articles.
Conclusions: Performing anal Pap smears is a valuable tool to detect cytologic changes associated with some strains of HPV infection. For persons participating in receptive anal intercourse, this diagnostic procedure provides the opportunity for early detection to guide appropriate follow-up and interventions.
Implications for practice: Appropriate screening can be incorporated easily into a primary care practice. High-risk groups that would benefit from this screening include men who have sex with men, HIV-infected men and women, immunocompromised men and women, women with a history of cervical or vulvar cancer (or high-grade cervical lesions), and women participating in receptive anal intercourse.