Disclosures The authors report no competing interests. To obtain CE credit for this activity, go to www.aanp.org and click on the CE Center. Locate the listing for this article and complete the post-test. Follow the instructions to print your CE certificate.
Systemic lupus erythematosus: A genetic review for advanced practice nurses
Article first published online: 27 NOV 2011
©2011 The Author(s) Journal compilation ©2011 American Academy of Nurse Practitioners
Journal of the American Academy of Nurse Practitioners
Volume 23, Issue 12, pages 629–637, December 2011
How to Cite
Robinson, M., Sheets Cook, S. and Currie, L. M. (2011), Systemic lupus erythematosus: A genetic review for advanced practice nurses. Journal of the American Academy of Nurse Practitioners, 23: 629–637. doi: 10.1111/j.1745-7599.2011.00675.x
- Issue published online: 7 DEC 2011
- Article first published online: 27 NOV 2011
- Received: February 2010;, accepted: September 2010
- SLE treatment;
- SLE management
Purpose: To review the symptom presentation, genetic aspects, and available treatment options for individuals diagnosed with systemic lupus erythematosus (SLE). Primary care providers should be vigilant in identifying symptoms, which may be related to SLE, perform adequate assessment, and diagnostic testing in order to arrive at an early diagnosis.
Data sources: Extensive literature review of textbook, clinical, medical, and nursing journals.
Conclusions: Lupus is a multigenic autoimmune disease, which requires the clinician to be hypervigilant by collecting a thorough family history and performing a complete physical assessment of the patient. There is an array of treatment modalities, both experimental and proven therapies, which improve signs and symptoms associated with SLE. Numerous medications are available for symptom management: anti-inflammatory agents for patients with musculoskeletal presentation, and steroids or antimalarials for those with more extensive organ involvement.
Implications for practice: In SLE, the overall aim of management is to determine the extent of disease and prevent extensive organ involvement. Therefore, when diagnosed in a timely manner, most patients will survive and are able to manage their disease.