Figure S1. Receptor Based Model where the dataset was aligned onto the template molecule 16 using the manual atom fit alignment.

Table S1. Summary of CoMFA statistical results for the GPR40 activity.

Table S2. Comparision of CoMSIA results for the ligand- and the receptor-based models.

Table S3. Observed and predicted pEC50 values of the diverse set of GPR40 agonists.

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