Insights into the Structural Requirements of PKCβII Inhibitors Based on HQSAR and CoMSIA Analyses
Version of Record online: 20 JUN 2011
© 2011 John Wiley & Sons A/S
Chemical Biology & Drug Design
Volume 78, Issue 2, pages 283–288, August 2011
How to Cite
Kumar, H., Kumar, R., Grewal, B. K. and Sobhia, M. E. (2011), Insights into the Structural Requirements of PKCβII Inhibitors Based on HQSAR and CoMSIA Analyses. Chemical Biology & Drug Design, 78: 283–288. doi: 10.1111/j.1747-0285.2011.01144.x
- Issue online: 13 JUL 2011
- Version of Record online: 20 JUN 2011
- Accepted manuscript online: 23 MAY 2011 07:59AM EST
- Received 12 February 2010, revised 6 July 2010 and accepted for publication 13 April 2011
Appendix S1. The data consists of following Layout, Tables and Figures: Layout 1. Some representative PKCβII inhibitors and extracted ligand. Table 1. Training and test set molecules with actual, predicted, and residuals values for HQSAR and CoMSIA analyses. Table 2. Statistical parameters for CoMSIA and HQSAR Model. Figure 1. A few fragments with positive and negative contributions to PKCβII inhibitory activity.
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