Re-use of this article is permitted in accordance with the Terms and Conditions set out at http://wileyonlinelibrary.com/onlineopen#OnlineOpen_Terms
Crizotinib-Resistant Mutants of EML4-ALK Identified Through an Accelerated Mutagenesis Screen
Article first published online: 31 OCT 2011
© 2011 John Wiley & Sons A/S
Chemical Biology & Drug Design
Volume 78, Issue 6, pages 999–1005, December 2011
How to Cite
Zhang, S., Wang, F., Keats, J., Zhu, X., Ning, Y., Wardwell, S. D., Moran, L., Mohemmad, Q. K., Anjum, R., Wang, Y., Narasimhan, N. I., Dalgarno, D., Shakespeare, W. C., Miret, J. J., Clackson, T. and Rivera, V. M. (2011), Crizotinib-Resistant Mutants of EML4-ALK Identified Through an Accelerated Mutagenesis Screen. Chemical Biology & Drug Design, 78: 999–1005. doi: 10.1111/j.1747-0285.2011.01239.x
- Issue published online: 16 NOV 2011
- Article first published online: 31 OCT 2011
- Received 26 July 2011, revised 29 August 2011 and accepted for publication 3 September 2011
Figure S1. Chemical structure of crizotinib and TAE684.
Figure S2. Impact of L1196M on anti-ALK activity of crizotinib and TAE684.
|CBDD_1239_sm_FigS1.tif||103K||Supporting info item|
|CBDD_1239_sm_FigS2a.tif||697K||Supporting info item|
|CBDD_1239_sm_FigS2b.tif||741K||Supporting info item|
|CBDD_1239_sm_Supplementaryfigurelegends.doc||22K||Supporting info item|
Please note: Wiley Blackwell is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.