Discovery of Novel Acyl Coenzyme A: Cholesterol Acyltransferase Inhibitors: Pharmacophore-Based Virtual Screening, Synthesis and Pharmacology
Article first published online: 27 APR 2012
© 2012 John Wiley & Sons A/S
Chemical Biology & Drug Design
Volume 80, Issue 1, pages 106–113, July 2012
How to Cite
Chhabria, M. T., Brahmkshatriya, P. S., Mahajan, B. M., Darji, U. B. and Shah, G. B. (2012), Discovery of Novel Acyl Coenzyme A: Cholesterol Acyltransferase Inhibitors: Pharmacophore-Based Virtual Screening, Synthesis and Pharmacology. Chemical Biology & Drug Design, 80: 106–113. doi: 10.1111/j.1747-0285.2012.01384.x
- Issue published online: 8 JUN 2012
- Article first published online: 27 APR 2012
- Accepted manuscript online: 16 MAR 2012 02:53PM EST
- Received 23 July 2011; revised 28 January 2012 and accepted for publication 25 February 2012
Chart S1. Chemical structures of training set compounds (1?21) with their IC50 values (in parentheses).
Chart S2. Chemical structures of test set compounds (22?46) with their IC50 values (in parentheses).
Chart S3. Structures of hits (47?54) found as query in virtual screening.
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