Novel Cruzain Inhibitors for the Treatment of Chagas’ Disease
Version of Record online: 27 JUN 2012
© 2012 John Wiley & Sons A/S
Chemical Biology & Drug Design
Volume 80, Issue 3, pages 398–405, September 2012
How to Cite
Rogers, K. E., Keränen, H., Durrant, J. D., Ratnam, J., Doak, A., Arkin, M. R. and McCammon, J. A. (2012), Novel Cruzain Inhibitors for the Treatment of Chagas’ Disease. Chemical Biology & Drug Design, 80: 398–405. doi: 10.1111/j.1747-0285.2012.01416.x
- Issue online: 23 JUL 2012
- Version of Record online: 27 JUN 2012
- Accepted manuscript online: 21 MAY 2012 07:22AM EST
- Received 14 March 2012, revised 28 April 2012 and accepted for publication 3 May 2012.
Figure S1. IC50 curves of each under various experimental conditions.
Table S1. Preliminary experimental validation results for compounds with IC50 values of 100 mMor lower.
Appendix S1. Description of experimental validation methods and assessment of non-specific inhibition via aggregation.
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