Ischemic bowel disease and risk of stroke: a one-year follow-up study

Authors

  • Jiunn-Horng Kang,

    1. Department of Physical Medicine and Rehabilitation, Taipei Medical University Hospital, Taipei, Taiwan
    2. Department of Physical Medicine and Rehabilitation, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
    Search for more papers by this author
  • Joseph J. Keller,

    1. School of Medical Laboratory Sciences and Biotechnology, Taipei Medical University, Taipei, Taiwan
    Search for more papers by this author
  • Herng-Ching Lin

    Corresponding author
    1. School of Health Care Administration, Taipei Medical University, Taipei, Taiwan
    • Correspondence: Herng-Ching Lin, School of Health Care Administration, College of Medicine, Taipei Medical University, 250 Wu-Hsing St., Taipei 110, Taiwan.

      E-mail: henry11111@tmu.edu.tw

    Search for more papers by this author

  • Disclosure: No conflict of financial interest to declare.
  • Funding: No funding source.

Abstract

Background

Ischemic bowel disease and stroke have been noted to have shared pathomechanisms. However, data regarding the stroke occurrence following ischemic bowel disease are still lacking.

Aim

The aim of this study is to explore the risk of stroke in patients with ischemic bowel disease during a one-year follow-up period in Taiwan.

Methods

Data used in this study were retrieved from the ‘Longitudinal Health Insurance Database 2000. Five hundred sixty-nine patients hospitalized with ischemic bowel disease were included as the study group, and 3414 subjects, matched by age and gender, were randomly extracted as a comparison group. Cox proportional hazards regression analysis was performed to test the relationship of ischemic bowel disease and subsequent stroke during the one-year follow-up period.

Results

The incidence rate of stroke among the sampled subjects during the 30-day, 90-day, and 365-day follow-up period was 1·24, 0·76, and 0·43 per 10 person-years. The adjusted hazard ratio for stroke for those patients with ischemic bowel disease within 30-, 90-, and 365-day follow-up periods was found to be 3·71 (95% confidence interval = 1·89–7·27), 2·11 (95% confidence interval = 1·22–3·66), and 1·70 (95% confidence interval = 1·14–2·52) times that of matched comparisons, respectively. The adjusted hazard ratio of ischemic stroke for patients with ischemic bowel disease was found to be 5·29 during the 30-day follow-up period than comparisons.

Conclusions

We found ischemic bowel disease to be significantly associated with stroke occurrence.

Ancillary