Letter to the editor
Definition of TIAs
Article first published online: 15 MAR 2013
© 2013 The Author. International Journal of Stroke © 2013 World Stroke Organization
International Journal of Stroke
Volume 8, Issue 3, page E5, April 2013
How to Cite
Norris, J. W. (2013), Definition of TIAs. International Journal of Stroke, 8: E5. doi: 10.1111/j.1747-4949.2012.00911.x
- Issue published online: 15 MAR 2013
- Article first published online: 15 MAR 2013
The authors of a recent article on thrombolytic therapy  advocate revising the definition of transient ischemic attack (TIA) based on recent advances in brain imaging. There have been several serious attempts to do this since the original description by Miller Fisher in 1958 , including that by a distinguished US neurological group in 2002  but none have withstood the ordeal of the test of time. The task is made all the more difficult by continuing advances in imaging over the years, so the definition would need to change from year to year.
Stroke and TIA were purely clinical definitions made decades before imaging was available, and so will never change in the foreseeable future. Progress in brain imaging will need to adapt accordingly and not the other way round.
- 1Thrombolytic therapy for acute ischemic stroke after recent transient ischemic attack. Int. J. Stroke 2012; 7:213–218., , et al.
- 2Intermittent cerebral ischemia; in Wright JS , Millikan CH (eds): Cerebral Vascular Disease. New York, Grune and Stratton, 1958:81–97..