Although recent epistemology has been marked by several prominent disagreements – e.g., between foundationalists and coherentists, internalists and externalists – there has been widespread agreement that some form of fallibilism must be correct. According to a rough formulation of this view, it is possible for a subject to have knowledge even in cases where the justification or grounding for the knowledge is compatible with the subject’s being mistaken. In this paper, I examine the motivation for fallibilism before providing a fully general account of the view. I conclude by looking at the two major difficulties for fallibilism: the Gettier problem and the lottery paradox.