For further information, contact: Martin C. Mahoney, MD, PhD, Roswell Park Cancer Institute, Elm & Carlton Streets, Buffalo, NY 14263; e-mail email@example.com.
Changes in Cancer Incidence Patterns Among a Northeastern American Indian Population: 1955-1969 Versus 1990-2004
Article first published online: 23 SEP 2009
© 2009 National Rural Health Association
The Journal of Rural Health
Volume 25, Issue 4, pages 378–383, Fall 2009
How to Cite
Mahoney, M. C., Va, P., Stevens, A., Kahn, A. R. and Michalek, A. M. (2009), Changes in Cancer Incidence Patterns Among a Northeastern American Indian Population: 1955-1969 Versus 1990-2004. The Journal of Rural Health, 25: 378–383. doi: 10.1111/j.1748-0361.2009.00247.x
- Issue published online: 23 SEP 2009
- Article first published online: 23 SEP 2009
ABSTRACT: Purpose:This manuscript examines shifts in patterns of cancer incidence among the Seneca Nation of Indians (SNI) for the interval 1955-1969 compared to 1990-2004. Methods: A retrospective cohort design was used to examine cancer incidence among the SNI during 2 time intervals: 1955-1969 and 1990-2004. Person-years at risk were multiplied by cancer incidence rates for New York State, exclusive of New York City, over 5-year intervals. A computer-aided match with the New York State Cancer Registry was used to identify incident cancers. Overall and site-specific standardized incidence ratios (SIRs = observed/expected × 100), and 95% confidence intervals (CIs), were calculated for both time periods. Results: During the earlier interval, deficits in overall cancer incidence were noted among males (SIR = 56, CI 36-82) and females (SIR = 71, CI 50-98), and for female breast cancers (SIR = 21, CI 4-62). During the more recent intervals, deficits in overall cancer incidence persisted among both genders (males SIR = 63, CI 52-77; females SIR = 67, CI 55-80). Deficits were also noted among males for cancers of the lung (SIR = 60, CI 33-98), prostate (SIR = 51, CI = 33-76) and bladder (SIR = 17, CI = 2–61) and among females for breast (SIR = 33, CI = 20-53) and uterus (SIR = 36, CI = 10-92). No cancer sites demonstrated increased incidence. Persons ages 60-69 years, 70-79 years, and ages 80+ years tended to exhibit deficits in overall incidence. Conclusions: Despite marked changes over time, deficits in overall cancer incidence have persisted between the time intervals studied. Tribal-specific cancer data are important for the development and implementation of comprehensive cancer control plans which align with local needs.