Although parental rearing of young is preferred, occasionally it is necessary to hand-rear animals to ensure their immediate health and long-term well-being. The hand-rearing techniques used at San Diego Zoo have been developed over 25 years. In May and October 1995 0.2 Mexican margays Leopardus wiedii glaucula were hand-reared at the Zoo. This paper documents the formula and feeding technique used. Details on the growth rate of the Mexican margays are compared to those of other felids.