This article describes the hand-rearing of a ♀ Two-toed sloth Choloepus didactylus from birth to its death at the age of 10 months. Developmental issues are discussed in detail, including diet, health, growth and weaning. The infant was successfully introduced to an adult ♀ in preparation for long-term pairing with a young 3. Socialization, integration and imprinting issues are also discussed. Retrospective analysis concluded that this was a worthwhile hand-rearing exercise that may he of benefit to others maintaining the species.