Weakness associated with spinal subpial myelopathy in a weimaraner puppy

Authors

  • P. S. V. COMONT,

    1. Wellcome Laboratory for Comparative Neurology, Department of Clinical Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge CB3 OES
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  • A. C. PALMER,

    1. Wellcome Laboratory for Comparative Neurology, Department of Clinical Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge CB3 OES
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  • A. E. WILLIAMS

    1. Wellcome Laboratory for Comparative Neurology, Department of Clinical Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge CB3 OES
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ABSTRACT

Clinical and pathological features are described in an eight-week-old weimaraner puppy which showed hindleg weakness and subpial myelin depletion in the spinal cord. The myelopathy was accompanied by pial thickening, vacuolation of sensory neurons in the spinal cord and of neurons in the medulla. Swollen axons occurred in the spinal cord, cerebellum and internal capsule. Comparisons are made between this case and a recently recorded form of hypomyelination in weimaraner dogs.

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