Histiocytic ulcerative colitis in boxer dogs in the UK

Authors

  • E. J. Hall,

    1. Departments of Veterinary Pathology, University of Liverpool, PO Box 147, Liverpool L69 3BX
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  • H. C. Rutgers,

    1. †Departments of Small Animal Medicine and Surgery, The Royal Veterinary College, University of London, Hawkshead Lane, North Mymms, Hatfield, Hertfordshire AL9 7TA
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  • S. F. E. Scholes,

    1. Departments of Veterinary Pathology, University of Liverpool, PO Box 147, Liverpool L69 3BX
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    • 2

      Lasswade Veterinary Laboratory, Bush Estate, Penicuik, Midlothian EH26 0SA

  • D. J. Middleton,

    1. ‡Departments of Pathology and Infectious Diseases, The Royal Veterinary College, University of London, Hawkshead Lane, North Mymms, Hatfield, Hertfordshire AL9 7TA
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    • 3

      School of Veterinary Science, University of Melbourne, Princes Highway, Werribee, Victoria 3000, Australia

  • B. J. Tennant,

    1. *Departments of Veterinary Clinical Sciences, University of Liverpool, PO Box 147, Liverpool L69 3BX
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  • N. M. King,

    1. *Departments of Veterinary Clinical Sciences, University of Liverpool, PO Box 147, Liverpool L69 3BX
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  • D. F. Kelly

    1. Departments of Veterinary Pathology, University of Liverpool, PO Box 147, Liverpool L69 3BX
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ABSTRACT

Histiocytic ulcerative colitis is an uncommon cause of canine large bowel diarrhoea that is generally refractory to standard treatment for idiopathic colitis. It is characterised pathologically by mucosal ulceration with a mixed inflammatory cell infiltrate, in which periodic acid-Schiff positive histiocytes are a dominant feature. The disease is well recognised in young boxer dogs in the USA, Australasia and mainland Europe. This paper reports the occurrence of seven cases of histiocytic ulcerative colitis seen recently in the UK, along with the clinical signs, histopathology, treatment and post mortem findings.

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