Comparison of two shampoos for treatment of Malassezia pachydermatis-associated seborrhoeic dermatitis in basset hounds

Authors

  • R. Bond,

    1. Dermatology Unit, Department of Small Animal Medicine and Surgery, The Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Hertfordshire AL9 7TA
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  • J. F. Rose,

    1. *J. F. Rose's present address is Department of Clinical Studies, Animal Health Trust, PO Box 5, Newmarket, Suffolk CB8 7DW
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  • J. W. Ellis,

    1. Dermatology Unit, Department of Small Animal Medicine and Surgery, The Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Hertfordshire AL9 7TA
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  • D. H. Lloyd

    1. Dermatology Unit, Department of Small Animal Medicine and Surgery, The Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Hertfordshire AL9 7TA
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ABSTRACT

A randomised double-blind parallel study compared the clinical and antimicrobial efficacies of a miconazole-chlorhexidine shampoo with a selenium sulphide shampoo for the treatment of seborrhoeic dermatitis associated with Malassezia pachydermatis in 33 basset hounds. All 16 miconazole-chlorhexidine treated hounds and 11 of 17 selenium sulphide treated hounds improved when shampooed at three-day intervals for three weeks. The miconazole-chlorhexidine treated hounds showed significantly greater reductions in pruritus (P<0·01), erythema (P<0·001), exudation (P<0·01) and overall severity (P<0·001), and in counts of M pachydermatis (P<0·001), total bacteria (P<0·001) and coagulase-positive staphylococci (P<0·001), when compared to the selenium sulphide treated group. Improvements in scaling and coat condition did not vary significantly between the two groups. These results indicate that seborrhoeic dermatitis in basset hounds is often associated with elevated

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