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The thoracic and abdominal radiographs of 84 dogs with multlcentric lymphoma were examined to identlfy the radiological abnormalities. The frequency of occurrence of individual changes, role of radiography in diagnosis, relationship of radiographic changes to hypercalcaemla and prognostic relevance of radiographic flndlngs were assessed. Multiple abnormalities were more commonly seen than solitary changes. No radiographic abnormalities were seen In approximately one quarter of thoracic radiographs and one fifth of abdominal radiographs. Lymphoma could not be diagnosed on the basis of radiographs alone. Many of the features of lymphoma were non-speclflc, having numerous possible causes. Cranial mediastinai disease was neither a prerequisite for, nor a disproportionately common flnding in, hypercaicaemic patients. The absence of radiological abnormalities may be a positive prognostic indicator but, in general, radiology had no place as a prognostic Indicator for the Individual patient. The differential diagnoses for the radlographlc abnormalities seen in lymphoma are discussed.