Department of Clinical Veterinary Medicine and Division of Veterinary Anaesthesia, University of Liverpool, Leahurst, Neston CH64 7TE
Subcutaneous pre-anaesthetic medication with acepromazine–buprenorphine is effective as and less painful than the intramuscular route
Article first published online: 16 SEP 2009
© 2009 British Small Animal Veterinary Association
Journal of Small Animal Practice
Volume 50, Issue 9, pages 474–477, September 2009
How to Cite
Gurney, M., Cripps, P. and Mosing, M. (2009), Subcutaneous pre-anaesthetic medication with acepromazine–buprenorphine is effective as and less painful than the intramuscular route. Journal of Small Animal Practice, 50: 474–477. doi: 10.1111/j.1748-5827.2009.00786.x
- Issue published online: 16 SEP 2009
- Article first published online: 16 SEP 2009
- Accepted: 17 April 2009
Objectives:To compare reaction to injection, sedation and propofol induction dose in dogs receiving acepromazine–buprenorphine pre-anaesthetic medication by the intramuscular or subcutaneous routes.
Methods:Fifty-two client owned dogs of American Society of Anesthesiologists grade I or II anaesthetised for diagnostic imaging. Dogs were randomly assigned to receive acepromazine 0·03 mg/kg and buprenorphine 0·02 mg/kg either intramuscular or subcutaneous. Reaction to injection was scored. Sedation was compared before and one hour after pre-anaesthetic medication. Propofol was administered in 1 mg/kg incremental injections until tracheal intubation was achieved. Total propofol dose was recorded.
Results:Reaction to injection was significantly greater (P=0·009) in the intramuscular group compared to the subcutaneous group. Sedation scores were not significantly different (P=0·523) between the intramuscular and the subcutaneous group. There was no statistically significant difference in propofol dose for induction (P=0·7).
Clinical Significance:Acepromazine–buprenorphine pre-anaesthetic medication provides a similar degree of sedation whether administered by the intramuscular or subcutaneous route. The intramuscular route is more painful compared to the subcutaneous route.