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Congenital mesoblastic nephroma in a young basset hound dog

Authors

  • S. Soldati,

    1. IDEXX-Diavet, Division of IDEXX Laboratories, Diavet-Labor AG, Bäch, Switzerland
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  • E. Radaelli,

    1. IDEXX-Diavet, Division of IDEXX Laboratories, Diavet-Labor AG, Bäch, Switzerland
    2. Department of Veterinary Pathology, Hygiene and Public Health, Faculty of Veterinary Medicine, Università degli Studi di Milano, Milano, Italy
    3. Mouse and Animal Pathology Lab, Fondazione Filarete, Milano, Milano, Italy
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  • A. Mazzuti,

    1. IDEXX-Diavet, Division of IDEXX Laboratories, Diavet-Labor AG, Bäch, Switzerland
    2. Clinica Veterinaria Alagia MarIa CarmelA, Ponte San Giovanni, Perugia, Italy
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  • E. Scanziani

    1. IDEXX-Diavet, Division of IDEXX Laboratories, Diavet-Labor AG, Bäch, Switzerland
    2. Department of Veterinary Pathology, Hygiene and Public Health, Faculty of Veterinary Medicine, Università degli Studi di Milano, Milano, Italy
    3. Mouse and Animal Pathology Lab, Fondazione Filarete, Milano, Milano, Italy
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ABSTRACT

An 18-month-old male basset hound was presented with vomiting, diarrhoea and depression. Abdominal ultrasonography revealed a mass in the left kidney. An ultrasound-guided core-biopsy indicated aggregates of spindle cells, but did not allow a definitive diagnosis. Nephrectomy was performed after a period of six months, when ultrasound examination revealed a slight increase in mass dimensions. Histologically the mass was composed of neoplastic spindle cells forming interlacing fascicles, bundles and whorls, within a loose myxoid to dense collagenous stroma. Immunohistochemically neoplastic cells were positive for vimentin and smooth muscle actin. Based on these findings the tumour was diagnosed as a congenital mesoblastic nephroma, classical variant. After a two-and-a-half-year follow-up the dog was clinically healthy, indicating a benign behaviour. To the authors’ knowledge, this report describes the first case of canine congenital mesoblastic nephroma successfully treated surgically, with a reasonable postsurgical follow-up.

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