Honaker's current address is Division of Marine Biology and Fisheries, Rosenstiel School of Marine and Atmospheric Science, University of Miami, FL, USA
Hyperascorbaemia in dogs admitted to a teaching hospital intensive care unit
Article first published online: 1 OCT 2012
© 2012 British Small Animal Veterinary Association
Journal of Small Animal Practice
Volume 53, Issue 11, pages 652–656, November 2012
How to Cite
Groth, E., Honaker, A., Osterbur, K., Deitschel, S. J., Odunayo, A. O., Chang, C.-H. and DeClue, A. (2012), Hyperascorbaemia in dogs admitted to a teaching hospital intensive care unit. Journal of Small Animal Practice, 53: 652–656. doi: 10.1111/j.1748-5827.2012.01290.x
- Issue published online: 2 NOV 2012
- Article first published online: 1 OCT 2012
- Accepted: 6 August 2012
To determine whether or not dogs develop a deficiency of ascorbic acid during hospitalisation in an intensive care unit.
Blood samples were collected daily for up to three days from dogs hospitalised in an intensive care unit for 36 to 72 hours (n = 16) or ê72 hours (n = 20) and from healthy dogs (n = 13). Plasma total ascorbic acid concentrations were measured using a colorimetric method involving a reaction between ascorbic acid, 2,6 dichlorophenol-indophenol, thiourea and dinitrophenyl hydrazine. Additionally, clinical data were recorded for each patient.
Dogs hospitalised for ê72 hours had significantly greater plasma ascorbic acid concentrations on day 3 compared to days 1 and 2. There was no difference in plasma ascorbic acid concentrations between days 1 and 2 for dogs hospitalised for 36 to 72 hours. Plasma ascorbic acid concentrations were significantly greater for each day of sampling for the hospitalised dogs compared to the control dogs.
Plasma ascorbic acid concentrations appear to increase during hospitalisation, and supplementation may not be indicated in dogs hospitalised in an intensive care unit.