Circulating natriuretic peptide concentrations in hyperthyroid cats

Authors


Abstract

OBJECTIVES

To assess the influence of thyroid function on natriuretic peptide concentration in hyperthyroid cats before and after treatment.

METHODS

Serum natriuretic peptide concentration was measured in 61 hyperthyroid cats recruited from first-opinion clinics before and after treatment.

RESULTS

Following successful treatment, total thyroxine, heart rate, systolic blood pressure and packed cell volume all decreased and bodyweight and creatinine concentrations increased. Furthermore, a significant (P < 0·001) decline in NT-proBNP concentration but not NT-proANP was identified.

CLINICAL SIGNIFICANCE

Thyroid function has a modest but significant effect on NT-proBNP concentration. Thyroid status should be taken into account when interpreting NT-proBNP concentrations in cats.

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