Translating Stem Cell Research: Challenges at the Research Frontier


  • David Magnus

    1. Director of the Stanford Center for Biomedical Ethics, and the Thomas A. Raffin Professor of Medicine and Biomedical Ethics and Professor of Pediatrics at Stanford University.
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This paper will address the translation of basic stem cell research into clinical research. While “stem cell” trials are sometimes used to describe established practices of bone marrow transplantation or transplantation of primary cells derived from bone marrow, for the purposes of this paper, I am primarily focusing on stem cell trials which are far less established, including use of hESC derived stem cells. The central ethical challenges in stem cell clinical trials arise in frontier research, not in standard, well-established areas of research.