Montelukast in allergic rhinitis: a systematic review and meta-analysis
Version of Record online: 2 OCT 2006
Volume 31, Issue 5, pages 360–367, October 2006
How to Cite
Grainger, J. and Drake-Lee, A. (2006), Montelukast in allergic rhinitis: a systematic review and meta-analysis. Clinical Otolaryngology, 31: 360–367. doi: 10.1111/j.1749-4486.2006.01276.x
- Issue online: 2 OCT 2006
- Version of Record online: 2 OCT 2006
- Accepted for publication 30 May 2006
• Allergic rhinitis is common.
• This systematic review outlines the evidence regarding montelukast in allergic rhinitis and provides a meta-analysis of its efficacy.
• The evidence suggests that montelukast does reduce nasal symptom score by 3.4% (95% CI: 2.5% to 4.2%) when compared with placebo.
• Montelukast is not as effective as topical nasal steroids or antihistamines and should therefore be regarded as second line therapy.
• When used, montelukast should be used in combination with an antihistamine.