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Evolution of Evolvabilitya


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    Our research is supported by grants from C.N.R.S., Ministère de la Recherche and Association pour la Recherche sur le Cancer. M. R. is currently professor at the Medical Faculty-Necker, University of Paris-V, France.

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ABSTRACT: Genomic sequence data provide evidence for a common origin of life and for its evolution by genetic variation via mutation and recombination. This paper discusses the fundamental dialectic paradigm of evolution-stability versus variability-at the crossroads of molecular genetics, population genetics, ecology, and the emerging science of experimental evolution. Experimental evolution of molecules, viruses, and bacteria can be used not only to test some basic evolutionary hypotheses but also to create new organisms for applications in biotechnology, agriculture, and medicine.