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The Burden of Drug-Resistant Tuberculosis and Mechanisms for Its Control


Address for correspondence: Mario Raviglione, World Health Organization, Communicable Diseases—StopTB, 20 Avenue Appia, CH 1211 Geneva 27, Switzerland;


Abstract: Drug resistance in tuberculosis is largely a man-made phenomenon caused by erroneous prescribing practices on the part of physicians and noncompliance on the part of patients. The global epidemiology of drug-resistant TB, the impact of standardized short-course chemotherapy (SSC), and the potential future evolution of MDR TB are discussed in this chapter.