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Hypothesis: The Protein Body Effect and Other Aspects of Food Matrix Effects

Authors

  • SUZANNE S. TEUBER

    Corresponding author
    1. Division of Rheumatology, Allergy and Clinical Immunology, University of California, Davis, School of Medicine, Davis, California 95616, USA
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Address for correspondence: Suzanne S. Teuber, M.D., Division of Rheumatology, Allergy and Clinical Immunology, University of California, Davis, School of Medicine, One Shields Avenue—TB 192, Davis, CA 95616. Voice: 530-752-4257; fax: 520-754-6047; ssteuber@ucdavis.edu.

Abstract

Abstract: With regard to the allergenicity of edible seeds and nuts, certain proteins may not be immediately accessible to digestion in the stomach and the upper small intestine because of the nature of the organization of such proteins into protein body organelles. Protein body hydration status, interactions between proteins, phytochemicals, protease inhibitors, and other matrix effects may contribute to the ability of a protein or package of proteins to reach the sites of active immune sampling in the gastrointestinal mucosa and thus be an influence on the potential allergenicity of a protein.

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