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Hypertension and Related Factors in the Etiology of Alzheimer's Disease

Authors

  • INGMAR SKOOG,

    Corresponding author
    1. Institute of Clinical Neuroscience, Section of Psychiatry, Sahlgrenska Hospital, Göteborg University, Göteborg, Sweden
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  • DEBORAH GUSTAFSON

    1. Institute of Clinical Neuroscience, Section of Psychiatry, Sahlgrenska Hospital, Göteborg University, Göteborg, Sweden
    2. Department of Nutrition and Food Sciences, Utah State University, Logan, Utah 84322-8700, USA
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Address for correspondence: Ingmar Skoog, M.D., Ph.D., Department of Psychiatry, Sahlgrenska University Hospital, SE-413 45 Göteborg, Sweden. Voice: +46 31 342 12 89; fax: +46 31 82 81 63; Ingmar.Skoog@neuro.gu.se.

Abstract

Abstract: The prevalence of hypertension is estimated to approach 50% in individuals above age 70. The consequences of hypertension include cerebrovascular disease, coronary heart disease, and general atherosclerosis. Several recent studies suggest that there may be an association also between hypertension and Alzheimer's disease (AD). This review will examine the evidence for this association and possible pathways between hypertension, Alzheimer encephalopathy, and clinical dementia.

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