ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
How reliable are the results from functional magnetic resonance imaging?
Article first published online: 20 MAR 2010
© 2010 New York Academy of Sciences
Annals of the New York Academy of Sciences
Volume 1191, The Year in Cognitive Neuroscience 2010 pages 133–155, March 2010
How to Cite
Bennett, C. M. and Miller, M. B. (2010), How reliable are the results from functional magnetic resonance imaging?. Annals of the New York Academy of Sciences, 1191: 133–155. doi: 10.1111/j.1749-6632.2010.05446.x
- Issue published online: 20 MAR 2010
- Article first published online: 20 MAR 2010
Functional magnetic resonance imaging (fMRI) is one of the most important methods for in vivo investigation of cognitive processes in the human brain. Within the last two decades, an explosion of research has emerged using fMRI, revealing the underpinnings of everything from motor and sensory processes to the foundations of social cognition. While these results have revealed the potential of neuroimaging, important questions regarding the reliability of these results remain unanswered. In this paper, we take a close look at what is currently known about the reliability of fMRI findings. First, we examine the many factors that influence the quality of acquired fMRI data. We also conduct a review of the existing literature to determine if some measure of agreement has emerged regarding the reliability of fMRI. Finally, we provide commentary on ways to improve fMRI reliability and what questions remain unanswered. Reliability is the foundation on which scientific investigation is based. How reliable are the results from fMRI?