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Keywords:

  • resveratrol;
  • aging;
  • vascular dysfunction

Cardiovascular diseases are the most common cause of death among the elderly in the Western world. Resveratrol (3,5,4′-trihydroxystilbene) is a plant-derived polyphenol that was shown to exert diverse anti-aging activity mimicking some of the molecular and functional effects of caloric restriction. This mini-review focuses on the molecular and cellular mechanisms activated by resveratrol in the vascular system, and explores the links between its anti-oxidative and anti-inflammatory effects, which could be exploited for the prevention or amelioration of vascular aging in the elderly.